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Theoretical and Computational Biology
Department of Biotechnology started the Bioinformatics in 1987 as one of the thrust areas of Biotechnology and the sustained support has given impetus to the development of Bioinformatics in the country through establishing the necessary infrastructure including the ‘Supercomputer’. Over the time being, bioinformatics has grown world over through contribution from various areas like Physics, Mathematics, Pharma sector and with the advent of new frontier area in Biotechnology like Genomics, Proteomics etc. As a result R&D activities in the relevant areas leads to massive inflow of data, which widens the scope of Bioinformatics, therefore, considering the international developments, the scope of the bioinformatics is broadened and with wider scope, Department of Biotechnology has designated ‘Bioinformatics’ as ‘Theoretical and Computational Biology (TCB)’.

The scope of the TCB will be as follows –

The task force on the theoretical and computational biology will encompass the Theoretical Biology, Bioinformatics and Computational biology in general. However, the scope also includes the Big Data Analysis and any futuristic development in the relevant areas.

The broad definitions of the subject areas are as follows:

Theoretical Biology (or Mathematical Biology or Biomathematics) is an interdisciplinary scientific research field for mathematical representation, treatment and modeling of biological processes using variety of mathematical tools and techniques. It has both theoretical and practical applications in biological, biomedical and biotechnology research.

Bioinformatics: Research, development, or application of computational tools and approaches for expanding the use of biological, medical, behavioral or health data, including those to acquire, store, organize, archive, analyze, or visualize such data.

Computational Biology: The development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems.

The various areas in which the DBT’s Bioinformatics activity winged out are as follows:


Dr T Madhan Mohan
Email: madhan[dot]dbt[at]nic[dot]in
Tel: 011-24362788

Programme Officers
Dr Gulshan Wadha
Email: Gulshan[dot]dbt[at]nic[dot]in
Tel: 011-24369612

Dr. Rajneesh K. Gaur (Programme Officer for TCB’s R&D activities)
Email: rajneesh[dot]gaur[at]nic[dot]in