This website your browser does not support. Please upgrade your browser Or Use google Crome
Latest Announcments
Other Links
DBT-ICMR Collaborative Effort on HIV/AIDS and Microbicides

Collaboration between DBT and ICMR was initiated through an MoU during 2007 to promote research in the HIV/AIDS and Microbicides area involving investigators from academia and research laboratories to design HIV antigens/antibodies/drugs/microbicides. The MoU was further extended during September, 2012 to pave the way for collaborative biomedical research and development of affordable technologies. One of such initiatives is the DBT-ICMR collaborative programme on “HIV/AIDS and Microbicides” which led efforts towards basic and translational research on immunopathogenesis of HIV and seeded efforts in development of therapeutic strategies. The 2nd phase of the programme has been taken up to accelerate the research efforts.

The overall objectives of the programme are

  • To accelerate research that will generate knowledge & develop technologies to provide the basis for the development of HIV vaccines & novel therapies against HIV including microbicides
  • To achieve more coordinated & impactful research in India towards a defined scientific mandate
  • To lay down priority areas & clinically achievable mandates that could encourage researchers of the country to contribute effectively & make a global impact towards HIV prevention related research activities.

Two subgroups are currently operational viz., Clinical Research Consortium and Natural Product Consortium on HIV/AIDS and Microbicides. Recently, pre-proposals were invited from interested researchers to study intricate relationships between HIV pathogenesis and immune defense in Long Term Non-Progressors (LTNPs) elite controllers (EC), HIV-Exposed Sero-negative (HESN) and High Risk Sero-negative cohorts.

Significant achievements made during the phase I of the programmes are as follows:

  • National Microbicides Testing centers established at NII (New Delhi) and NARI (Pune). In-vitro screening assays have been developed for evaluation of microbicides.
  • Several lead compounds with potential anti-HIV activity identified from plant sources.
  • Herbal microbicide ‘BASANT’ has completed Phase –I clinical trials with encouraging results.
  • Virtual Knowledge Resource Center (VKRC) is functional at NARI, Pune.
  • Novel mechanism of resistance and potential therapeutic targets identified.